The crew members returned to Sheppard Air Force Base, Texas, following the crash, according to the post, adding that they were on a pilot instructor training mission at the time of the accident.
Base officials did not provide additional details on the status of the pilots, and refused to provide any other information about the mishap to Military.com on Thursday, stating that an investigation into the cause is underway.
Officials are asking anyone "who may find debris in the area that may be related to the accident" to contact the Sheppard Command Post at (940) 676-2616.
"For safety reasons, please do not touch or move the material," officials said.
The crash occurred shortly before 2 p.m. Wednesday near Lake Waurika, Oklahoma, roughly 40 miles from the training base. Emergency crews responded to the scene.
In September, leaders called for a "brief pause" following a crash involving a T-6 from Joint Base San Antonio-Randolph, Texas.
That trainer went down roughly 30 miles from the base Sept. 18. The crew ejected safely and sustained minor injuries, officials said at the time.
The pause was lifted a few days later.